Trends in Clinical and Medical Sciences
Special issue: Recent developments of medical and surgical research (2023), pp. 250 – 254
ISSN: 2791-0814 (online) 2791-0806 (Print)
DOI: 10.30538/psrp-tmcs2023.si-rdmsr034
ISSN: 2791-0814 (online) 2791-0806 (Print)
DOI: 10.30538/psrp-tmcs2023.si-rdmsr034
A study of causes of thrombocytopenia in pregnancy and its effect on maternal outcome
Niharika Singh\(^{1,*}\) and Sharvari Vikramsinha Jadhav\(^{1}\)
\(^{1}\) Department of Obstetrics and Gynaecology, Bharati Vidyapeeth (Deemed to be University) Medical College and Hospital, Sangli, Maharashtra, India.
Correspondence should be addressed to Niharika Singh at dr.singh.niharika@gmail.com
Copyright © 2023 Niharika Singh and Sharvari Vikramsinha Jadhav. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: February 2, 2023 – Accepted: April 12, 2023 – Published: April 17, 2023
Abstract
Background: Pregnancy is associated with numerous physiological and pathological changes. Thrombocytopenia, defined as a platelet count of less than 150,000/\(\mu\)L, is the second most common hematological finding in pregnancy after anemia. It may manifest during pregnancy and increase the risk of bleeding.
Materials & Methods: This prospective observational study was carried out in the Antenatal outpatient and inpatient Department of Gynecology and Obstetrics at Bharati Vidyapeeth Medical College and Hospital, Sangli. All pregnant women diagnosed with thrombocytopenia during the six-month study period were included. Patients were followed until delivery to record any complications such as preterm labor, abruption, preeclampsia, postpartum hemorrhage, or any other morbidities, and to determine maternal outcomes.
Results: Out of 246 pregnant patients, 30 were found to have thrombocytopenia with a platelet count of 150,000/mm\(^3\) or below, giving a prevalence of approximately 12%. The cases were recorded based on demographic characteristics, gestational age at the time of first onset of thrombocytopenia, severity of thrombocytopenia, and any intervention. Maternal outcomes were recorded.
Conclusion: Gestational thrombocytopenia is the most common cause of thrombocytopenia during pregnancy and has good maternal outcomes. Managing pregnant women with platelet disorders requires a multidisciplinary approach and close collaboration between obstetricians and hematologists.
Materials & Methods: This prospective observational study was carried out in the Antenatal outpatient and inpatient Department of Gynecology and Obstetrics at Bharati Vidyapeeth Medical College and Hospital, Sangli. All pregnant women diagnosed with thrombocytopenia during the six-month study period were included. Patients were followed until delivery to record any complications such as preterm labor, abruption, preeclampsia, postpartum hemorrhage, or any other morbidities, and to determine maternal outcomes.
Results: Out of 246 pregnant patients, 30 were found to have thrombocytopenia with a platelet count of 150,000/mm\(^3\) or below, giving a prevalence of approximately 12%. The cases were recorded based on demographic characteristics, gestational age at the time of first onset of thrombocytopenia, severity of thrombocytopenia, and any intervention. Maternal outcomes were recorded.
Conclusion: Gestational thrombocytopenia is the most common cause of thrombocytopenia during pregnancy and has good maternal outcomes. Managing pregnant women with platelet disorders requires a multidisciplinary approach and close collaboration between obstetricians and hematologists.
Keywords:
Anemia; Platelets; Pregnancy; Thrombocytopenia.