Trends in Clinical and Medical Sciences

A retrospective study of clinico-pathologic patterns, in women below 40 years, with ovarian cancer

Dr. Abirami M.D.
Assistant Professor, Department of Obstetrics and Gynecology, Srinivasan Medical College Hospital and Research Centre, Trichy; dr.abirami@gmail.com

Abstract

Objectives and methods: The present study is a Prospective study of clinico-pathologic patterns, in women 40 years and below, with ovarian cancer undertaken in Srinivasan Medical College Hospital and Research Centre over a period of 36 months.
Inclusion Criteria: Patients $\leq$ 40 years with histologically proven ovarian cancer and Primary ovarian cancers \textbf{Exclusion Criteria:} Patients above age 40 years, Those who did not have cancer ovary on final histopathology, Patients who were treated with chemotherapy only and not operated. 115 patients were retrospectively enlisted for our study out of which 93 could fulfil our inclusion criteria.
Results and conclusion: Even in women 40 years and less, 70% of the ovarian tumors were epithelial in histological type. Serous ovarian cancer was the most common. Germ cell tumor constituted 20% of the ovarian cancers. Mixed malignant germ cell tumor was the commonest type. The mean overall survival was 5.4 years. The overall survival was 87%. For epithelial tumors it was 82% and for non-epithelial tumors it was 96%. For early stage disease it was 100% but for advanced stages it was 73%.

Keywords:

Ovarian cancer; Ovarian malignancy; Ovarian tumors; Clinico pathology.