Trends in Clinical and Medical Sciences

Justification of the expediency of using light propylene nets for onlay plastic surgery of postoperative ventral hernias

K. F. Zuparov\(^{1,*}\), N. Ya Fayzullayeva\(^{2}\) and A. A. Tursumetov\(^{3}\)
\(^{1}\) Tashkent Pediatric Medical Institute Tashkent, Uzbekistan.
\(^{2}\) Institute of Immunology and Human Genome of the Academy of Sciences of the Republic of Uzbekistan Tashkent, Uzbekistan.
\(^{3}\) Tashkent Pediatric Medical Institute Tashkent, Uzbekistan.
Correspondence should be addressed to K. F. Zuparov at liddin89l@mail.ru

Abstract

This article discusses the feasibility of using lightweight polypropylene nets for onlay plastic surgery of postoperative ventral hernias (POVH). The study involved 137 patients with POVH, who were divided into two groups: the control group (64 patients) who underwent traditional Esfil-heavy mesh endoprosthesis and the primary group (73 patients) who received Esfil-light endoprostheses. The study investigated the clinical and immunological aspects of using propylene nets in these two groups of patients. Before surgery, the examined patients showed a suppression of the cellular link of immunity, an imbalance of the humoral link, and non-specific factors of protection. The use of polypropylene meshes (Esfil-light and Esfil-heavy) triggered an inflammatory reaction associated with the structural properties of the prostheses. However, the use of Esfil-light PP prosthesis in onlay allogernioplasty caused less inflammation in the alloplasty area compared to Esfil-heavy. Overall, the findings suggest that Esfil-light PP prosthesis can be a suitable alternative to traditional Esfil-heavy mesh endoprosthesis for onlay plastic surgery of postoperative ventral hernias. The reduced inflammatory reaction in the alloplasty area may lead to improved outcomes for patients undergoing this procedure.

Keywords:

Ventral hernia; Polypropylene mesh; Onlay surgery; Immunological response; Allogernioplasty.