Trends in Clinical and Medical Sciences
Special issue: Indian Medical Research Views and Findings on Last 5 years (2023), pp. 250 – 254
ISSN: 2791-0814 (online) 2791-0806 (Print)
DOI: 10.30538/psrp-tmcs2023.si-imrv039
ISSN: 2791-0814 (online) 2791-0806 (Print)
DOI: 10.30538/psrp-tmcs2023.si-imrv039
To study the levels of cytokines in metabolic syndrome and non-metabolic syndrome individuals
Abdul Rab Alli\(^{1}\), Dr. Shreya Nigoskar\(^{2}\) and Doddigarla Zephy\(^{3*}\)
\(^{1}\) Ph.D. Scholar Department of Biochemistry, Index Medical college & Research Centre, Malwanchal University, Indore.
\(^{2}\) Professor & Head of the Department, Department of Biochemistry, Index Medical college & Research Centre, Malwanchal University, Indore.
\(^{3}\) Associate Professor, Department of Biochemistry, Hi-Tech Medical College & Hospital, Rourkela.
Correspondence should be addressed to Doddigarla Zephy at drzephy@gmail.com
Copyright © 2023 Abdul Rab Alli, Dr. Shreya Nigoskar and Doddigarla Zephy. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: March 1, 2023 – Accepted: May 25, 2023 – Published: May 26, 2023
Abstract
Background: Metabolic syndrome is characterized by abnormalities in blood pressure, blood sugar, waist circumference, and cholesterol or triglyceride levels.
Aim: The unique aspect of this study is its primary focus on determining whether there is a distinction in inflammatory markers between individuals with metabolic syndrome and those without the condition.
Material and Methods: The study included 50 patients with metabolic syndrome and 50 healthy controls. The research was conducted at Indore Index Medical College & Research Centre. After obtaining approval, the study’s researchers commenced their work. Each subject provided informed consent prior to the study. Individuals with type 1 diabetes or clinical symptoms for fewer than five years and documented T2DM duration were excluded. Healthy controls (non-metabolic syndrome) were individuals without diabetes, multivitamin use, or comorbidities.
Statistical analysis: Regressions were used to determine the relationship between two variables. Additionally, percentages were calculated. A significance level of \(p < 0.05\) was considered significant.
Conclusion: The significance of these results cannot be overstated. The study’s findings unequivocally demonstrate that both pro-inflammatory and anti-inflammatory cytokines contribute to the development of secondary illnesses associated with metabolic syndrome.
Aim: The unique aspect of this study is its primary focus on determining whether there is a distinction in inflammatory markers between individuals with metabolic syndrome and those without the condition.
Material and Methods: The study included 50 patients with metabolic syndrome and 50 healthy controls. The research was conducted at Indore Index Medical College & Research Centre. After obtaining approval, the study’s researchers commenced their work. Each subject provided informed consent prior to the study. Individuals with type 1 diabetes or clinical symptoms for fewer than five years and documented T2DM duration were excluded. Healthy controls (non-metabolic syndrome) were individuals without diabetes, multivitamin use, or comorbidities.
Statistical analysis: Regressions were used to determine the relationship between two variables. Additionally, percentages were calculated. A significance level of \(p < 0.05\) was considered significant.
Conclusion: The significance of these results cannot be overstated. The study’s findings unequivocally demonstrate that both pro-inflammatory and anti-inflammatory cytokines contribute to the development of secondary illnesses associated with metabolic syndrome.
Keywords:
Metabolic syndrome; Tumor necrosis factor; Cytokines; Body mass index; Inflammation.