Trends in Clinical and Medical Sciences
Special issue: Recent developments of medical and surgical research (2023), pp. 315 – 320
ISSN: 2791-0814 (online) 2791-0806 (Print)
DOI: 10.30538/psrp-tmcs2023.si-rdmsr043
ISSN: 2791-0814 (online) 2791-0806 (Print)
DOI: 10.30538/psrp-tmcs2023.si-rdmsr043
Spectrum of thrombocytopenia in febrile ill children along with its clinical manifestations in a tertiary health care centre-A descriptive study
Sonali Bandil\(^{1,*}\), Anish Kumar\(^1\), Shruti Singh\(^1\), Rajesh Gaur\(^2\), Naushad Hussain\(^1\) and Chandramani Yadav\(^3\)
\(^{1}\) Department of Pathology, Autonomous Government State Medical College, Firozabad, Uttar Pradesh-283203, India.
\(^2\) Department of Pathology, GajraRaja Medical College, Gwalior, Madhya Pradesh, India.
\(^3\) Department of Community Medicine, Autonomous Government State Medical College, Firozabad, Uttar Pradesh, India.
Correspondence should be addressed to Sonali Bandil at oct29sonalibandil@gmail.com
Copyright © 2023 Sonali Bandil, Anish Kumar, Shruti Singh, Rajesh Gaur, Naushad Hussain and Chandramani Yadav. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: December 1, 2022 – Accepted: April 20, 2023 – Published: April 29, 2023
Abstract
Introduction: Fever with thrombocytopenia is a common clinical presentation among patients in tertiary care hospitals. Various etiologies, such as malaria, dengue, leptospirosis, typhoid, miliary tuberculosis, and septicemia, are the common causes of fever with thrombocytopenia.
Aim: This study aimed to determine the various etiologies of febrile illness in children with thrombocytopenia, study their bleeding and clinical manifestations, and examine their correlation with the severity of platelet count.
Materials and methods: This study included 1000 pediatric patients with thrombocytopenia between January 2021 and December 2021 at an autonomous state medical college in Firozabad, Uttar Pradesh.
Results: In our study, the most common etiology was dengue, followed by sepsis and hematological malignancies. The most common age group of patients was 10-15 years. The severity of cases was determined based on the grading of thrombocytopenia and bleeding and clinical manifestations. Fever and myalgia were the most common clinical presentations of patients with thrombocytopenia.
Conclusion: Platelet count is a good predictor of bleeding manifestations due to severe thrombocytopenia, which can lead to life-threatening conditions. Prompt diagnosis is crucial to start treatment as soon as possible, including platelet transfusions for patients.
Aim: This study aimed to determine the various etiologies of febrile illness in children with thrombocytopenia, study their bleeding and clinical manifestations, and examine their correlation with the severity of platelet count.
Materials and methods: This study included 1000 pediatric patients with thrombocytopenia between January 2021 and December 2021 at an autonomous state medical college in Firozabad, Uttar Pradesh.
Results: In our study, the most common etiology was dengue, followed by sepsis and hematological malignancies. The most common age group of patients was 10-15 years. The severity of cases was determined based on the grading of thrombocytopenia and bleeding and clinical manifestations. Fever and myalgia were the most common clinical presentations of patients with thrombocytopenia.
Conclusion: Platelet count is a good predictor of bleeding manifestations due to severe thrombocytopenia, which can lead to life-threatening conditions. Prompt diagnosis is crucial to start treatment as soon as possible, including platelet transfusions for patients.
Keywords:
Dengue fever; Platelet count; National cancer Institute.