Trends in Clinical and Medical Sciences
Special issue: Recent developments of medical and surgical research (2023), pp. 238 – 241
ISSN: 2791-0814 (online) 2791-0806 (Print)
DOI: 10.30538/psrp-tmcs2023.si-rdmsr032
ISSN: 2791-0814 (online) 2791-0806 (Print)
DOI: 10.30538/psrp-tmcs2023.si-rdmsr032
To justify thyroid abnormalities in aub among reproductive age group: A prospective study
R. Abirami\(^{1}\) and N. Naveetha Lakshmi\(^{2,*}\)
\(^{1}\) Department of obstetrics and Gynecology, Srinivasan Medical College Hospital and Research Centre, Trichy.
\(^{2}\) Department of Biochemistry, Dhanalakshmi Srinivasan Medical College Hospital, Perambalur.
Correspondence should be addressed to N. Naveetha Lakshmi at drnaveetha@gmail.com
Copyright © 2023 R. Abirami and N. Naveetha Lakshmi. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: December 29, 2022 – Accepted: April 1, 2023 – Published: April 16, 2023
Abstract
Objectives and methods: The present study is a cross-sectional study of 250 women with abnormal uterine bleeding in the reproductive age group undertaken in Srinivasan Medical college Hospital and Research centre over a period of 12 months. It was done to ascertain the possibility of a correlation between subclinical thyroid dysfunction and AUB.
Results and conclusion: The incidence of thyroid dysfunction in the reproductive age group is 1-2%. It is 10 times more common in women than in men. The incidence of thyroid dysfunction in a population with AUB is 20.4% according to our study and hence selective screening of this population would result in a higher yield. The study showed a significant correlation (p= 0.019, significant) between increasing age and thyroid dysfunction. TSH is a good screening test with a sensitivity of 72% and specificity of 100%. The positive and negative predictive values were 100% and 91% respectively.
Results and conclusion: The incidence of thyroid dysfunction in the reproductive age group is 1-2%. It is 10 times more common in women than in men. The incidence of thyroid dysfunction in a population with AUB is 20.4% according to our study and hence selective screening of this population would result in a higher yield. The study showed a significant correlation (p= 0.019, significant) between increasing age and thyroid dysfunction. TSH is a good screening test with a sensitivity of 72% and specificity of 100%. The positive and negative predictive values were 100% and 91% respectively.
Keywords:
Thyroid dysfunction; abnormal uterine bleeding; AUB; TSH; Thyroid profile.