Histopathological patterns in the endometrial biopsy of patients presenting with abnormal uterine bleeding
Abstract: Aim: To assess histopathological patterns in the endometrial biopsy of patients presenting with abnormal uterine bleeding.
Methodology: One hundred eight females with the complaint of abnormal uterine bleeding were enrolled. A gynecological examination was done. Dilatation and curettage were carried out. Specimens thus obtained were stored in 10\% formalin. The slides were examined under a microscope, and the various histopathological patterns were assessed.
Results: The age group 20-30 years had 48, 30-40 years had 50, and 40-50 years had ten females. A significant difference was observed. Inflammatory lesions were 28, such as acute endometritis in 12, chronic endometritis in 11, and chorioamnionitis in 5. Proliferative non-neoplastic lesions were 42, such as atypical hyperplasia in 18, typical hyperplasia in 12, and endometrial polyp in 12. Neoplastic lesions in 20 include leiomyoma in 8, a partial mole in 7, the complete mole in 2, and endometroid carcinoma in 3. Normal endometrium in 18, such as proliferative phase in 12 and secretory phase endometrium in 6. A significant difference was observed (P< 0.05).
Conclusion: The most common endometrial biopsy revealed proliferative non-neoplastic lesions such as atypical hyperplasia, typical hyperplasia, and endometrial polyp.