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Latest Published Articles
OMS-Vol. 3 (2019), Issue 1, pp. 191 – 197 Open Access Full-Text PDF
Elmetwally M. Elabbasy, Ethiraju Thandapani, Osama Moaaz, Omar Bazighifan
Abstract: This work is concerned with the oscillatory behavior of fourth-order delay differential equation with middle term. By using the generalized Riccati transformations and new comparison principles, we establish new oscillation results for this equation. An example illustrating the results is also given.
Book graphs are cycle antimagic
OMS-Vol. 3 (2019), Issue 1, pp. 184 – 190 Open Access Full-Text PDF
Muhammad Awais Umar, Noshad Ali, Afshan Tabassum, Basharat Rehman Ali
Abstract: Let \(G=(V,E)\) be a finite simple graph with \(v =|V(G)|\) vertices and \(e=|E(G)|\) edges. Further suppose that \(\mathbb{H}:=\{H_1, H_2, \dots, H_t\}\) is a family of subgraphs of \(G\). In case, each edge of \(E(G)\) belongs to at least one of the subgraphs \(H_i\) from the family \(\mathbb{H}\), we say \(G\) admits an edge-covering. When every subgraph \(H_i\) in \(\mathbb{H}\) is isomorphic to a~given graph \(H\), then the graph \(G\) admits an \(H\)-covering. A graph \(G\) admitting \(H\) covering is called an \((a,d)-H\)-antimagic if there is a bijection \(\eta:V\cup E \to \{1,2,\dots, v+e \}\) such that for each subgraph \(H’\) of \(G\) isomorphic to \(H\), the sum of labels of all the edges and vertices belongs to \(H’\) constitutes an arithmetic progression with the initial term \(a\) and the common difference \(d\). For \(\eta(V)= \{ 1,2,3,\dots,v\}\), the graph \(G\) is said to be super \((a,d)-H\)-antimagic and for \(d=0\) it is called \(H\)-supermagic. When the given graph \(H\) is a cycle \(C_m\) then \(H\)-covering is called \(C_m\)-covering and super \((a,d)-H\)-antimagic labeling becomes super \((a,d)-C_m\)-antimagic labeling. In this paper, we investigate the existence of super \((a,d)-C_m\)-antimagic labeling of book graphs \(B_n\), for \(m=4,\ n\geq2\) and for differences \(d=1, 2, 3, \dots,13\).
Anti-proliferative and migratory inhibition study of b16f10 in mouse melanoma cells induced by synthetic indole-oxadiazole bearing butanamides
OJC-Vol. 2 (2019), Issue 1, pp. 21 – 29 Open Access Full-Text PDF
Muhammad Athar Abbasi, Seong-Hui Eo, Aziz-ur-Rehman, Sabahat Zahra Siddiqui, Yohan Han, Seon-Mi Yu, Song Ja Kim, Mubashir Hassan, Hussain Raza, Syed Anan Ali Shah, Sung-Yum Seo
Abstract: Matrix metalloproteinases-2 and -9 (MMP-2/-9) are key tissue remodeling enzymes that have multiple overlapping activities critical for wound healing and tumor progression. In search of new anti-tumor agents, indole-oxadiazole containing butanamides (1-5) were evaluated with B16F10 mouse melanoma cells in this study. The results showed that compounds 1, 2 and 3 inhibited the cell proliferation in a considerable manner at concentrations ranging from 0-44M. The possible migration inhibitory effects of these melanoma cells were further evaluated through gelatinolytic activity of MMP-2 and MMP-9 secreted from B16F10 cells and it was inferred that compounds 1, 2 and 3 affected the expression and activity of these enzymes in a dose dependent manner while compound 1 can be regarded as promising anti-tumor agent.
Synthesis of nickel nanoparticles by sol-gel method and their characterization
OJC-Vol. 2 (2019), Issue 1, pp. 16 – 20 Open Access Full-Text PDF
Aisha Shamim, Zaheer Ahmad, Sajid Mahmood, Umair Ali, Tariq Mahmood, Zamir Ahmad Nizami
Abstract: The under consideration study focuses on synthesis and characterization of Nickel oxide (NiO) nanoparticles. Nanosized Nickel oxide powder was successfully synthesized using a simple and low cast sol-gel method. This method is environment friendly requiring no expensive chemicals and is time saving. The sol-gel method was accompanied by the formation of precipitates which were dried and calcined at 550\(^{o}\)C to get nickel oxide nanoparticles. The synthesized nanopowder was characterized by X-ray diffraction (XRD), Scanning Electron Microscopy (SEM), and Energy Dispersive Spectroscopy (EDX).
Graphene oxide synthesis by facile method and its characterization
OJC-Vol. 2 (2019), Issue 1, pp. 11 – 15 Open Access Full-Text PDF
Farman ullah Khan, Sajid Mahmood, Zaheer Ahmad, Tariq Mahmood, Zamir Ahmad Nizami
Abstract: The graphene and graphene oxide are latest and advanced materials with wide applications in environment, medical applications, industries, defense applications. We have synthesized graphene oxide from graphite flakes by modifying Hummer method in which we used NaNO\(_{2}\) instead of NaNO\(_{3}\). Then we characterized our samples with X-Ray Diffractometry (XRD), Scanning-Electron Microscopy (SEM) and Fourier-Transform Infrared-Spectroscopy (FT-IR). These results confirmed the formation of graphene oxide also through this process. This graphene oxide can further be used for future applications in wastewater treatment and biomedical applications.
Synthesis, spectral evaluation and pharmacological screening of some sulfa drugs
OJC-Vol. 2 (2019), Issue 1, pp. 1 – 10 Open Access Full-Text PDF
Aziz-Ur-Rehman, Muhammad Athar Abbasi, Sabahat Zahra Siddiqui, Shahid Rasool, Sadia Jabeen, Amar Masood Joyia, Asma Salah-Ud-Din Gondal
Abstract: Sulfonamides are considered to be biologically active and an important class of pharmaceutical compounds. These constitute an important class of antimicrobials, antidiabetics, anticancer and diuretics. These were the first chemotherapeutic drugs introduced to the world but their rapidly developed resistance decreased their use. In the present work, N-(2/4-substitutedphenyl)-4-(substituted)benzenesulfonamide (3a-d) and N-(tetrahydrofuran-2-ylmethyl)-4-methylbenzenesulfonamide 3e were synthesized by the reaction of substituted aniline (1a-c) and tetrahydrofuran-2-ylmethanamine (1d) with substituted benzenesulfonyl chloride (2a-d) using 10% aqueous \(Na_{2}CO_{3}\) solution as a reaction medium. In the second step, the synthesized molecules 3a-e were allowed to react different alkyl/aralkyl halides (4a-j) to synthesize the target N-substituted compounds, 5a-z,aa,bb, using lithium hydride as an activator and N,N-dimethylformamide (DMF) as a reaction medium. All the synthesized compounds were characterized by using spectral techniques such as \(^{1}\)H-NMR, IR and EI-MS; and further examined for their anti-bacterial activities.